Brisdelle Overview

Brisdelle, a low dose of seven.5 mg of paroxetine as a mesylate salt, is a new prescription medication that has been developed specifically to scale back hot flashes caused by menopause. The development of this medication happened once doctors noticed that breast cancer patients who were mistreatment numerous antidepressants were experiencing fewer hot flashes. Once studies of paroxetine were conducted, the effects shown that this medicine was effective in treating hot flashes in menopausal women.


Active Ingredients

• Paroxetine
• SSRI (GlaxoSmithKline)
• Pexeva (Noven Therapeutics)


Brisdelle comes as a pill that contains 7.5mg of paroxetine. It’s taken once daily at time of day.


  • Brisdelle could be a FDA approved drug to reduce menopause signs.
  • It is also clinically tested.
  • It is a Non-hormonal medication to solve menopausal issues.


  • It is a New and not time-tested.
  • There is indication of the bigger risk of hazardous thought on the drug’s label.
  • It will reduce the efficiency of the carcinoma drug estrogen antagonist.

 Brisdelle’s Caveats and Precautions

  • Suicidality: All patients being cured with BRISDELLE ought to be determined closely for clinical worsening, suicidality, and strange changes in behavior, particularly throughout the initial few months of treatment.
  • Serotonin Syndrome: Serotonin syndrome, that is doubtless serious, has been rumored with concomitant use of serotonergic medicine, and with drugs that impair metabolism of serotonin (in explicit, MAOIs). Monitor patients for the emergence of serotonin syndrome. Stop BRISDELLE and any associated serotonergic agents and initiate validating treatment.
  • Tamoxifen: Efficacy of tamoxifen may be reduced once administered concomitantly with BRISDELLE.
  • Abnormal Bleeding: SSRIs, as well as BRISDELLE, could increase the chance of bleeding events. Caution patients regarding the chance of bleeding related to the concomitant use of BRISDELLE and non-steroidal anti-inflammatory drug medicine (NSAIDs), aspirin, or alternative medicine that affect coagulation.
  • Hyponatremia: May occur as a results of treatment with SSRIs, together with BRISDELLE. Senior patients could also be at larger risk and in several cases it will occur in association with syndrome of inappropriate hormone secretion (SIADH). Think about discontinuation of BRISDELLE in patients with symptomatic symptom and institute applicable medical intervention.
  • Bone fracture: Epidemiological studies have reported an association between SSRIs treatment and fractures.
  • Activation of Mania/Hypomania: Screen for bipolar disorder and monitor for mania/hypomania.
  • Seizures: Use carefully in patients with a history of appropriations or with conditions that potentially lower the seizure threshold.
  • Akathisia: Will occur, presumably within the first few weeks of treatment. Discontinue treatment with BRISDELLE if akathisia happens.
  • Acute Angle Closure Glaucoma: May cause acute angle closure in patients with narrow angle glaucoma; tell patients with narrow angle glaucoma to report visual symptoms.
  • Cognitive and Motor Impairment: Could cause impairment; patients shouldn’t operate machinery or cars till bound that BRISDELLE doesn’t have an effect on them adversely.

Adverse Reactions

The most common adverse reactions (≥2%) rumored in clinical trials were pain, tiredness, and nausea and vomiting. Of these, nausea occurred primarily inside the first four weeks of treatment and fatigue occurred primarily inside the first week of treatment, and reduced in occurrence with constant therapy.

Final Word

As with any new medication, refer to your doctor regarding whether or not this drug is right for you. Bound health conditions and medications could forestall the utilization of Brisdelle. You and your health provider can need to weigh the benefits and risks of this medication to work out if it’s right for you.

Reverse The Symptoms Of Menopause With Menersa
If the symptoms of menopause are controlling your life, Menersa may be the key to becoming comfortable again. Each and every day, roughly 4,000 women are reaching menopause. It would seem like this should be an exciting time of your life. The symptoms of menopause are making this a difficult time for many women. Now everyone know that Menersa is a natural, secret weapon against the symptoms of menopause!

The Drawbacks of Menopause
What symptoms does most menopausal women experience?

  •     Weight Gain
  •     Hot Flashes
  •     Night Sweats
  •     Mood Swings
  •     Vaginal Dryness
  •     Urinary Problems
  •     Decrease in Sex Drive

About Menopause and PeriMenopause
As we women age, we all will have to face menopause. Menopause is a term that covers the changes women experience just before or after they stop menstruating. Women are born with a certain number of eggs, which the ovaries store. The hormones estrogen and progesterone are produced by the ovaries, and they regulate ovulation and menstruation. Menopause happens when the ovaries no longer create an egg each month, and monthly menstruation ceases. You are moving on to the next stage of adulthood. But the reward is not felt by quite a few.

How Menersa Can Change Your Life
Menersa is exactly the natural, effective hormone replacement therapy that menopausal women are seeking. Menersa provides natural, proven relief for the irritating symptoms of menopause.

  •     Balances Hormone Levels
  •     Promotes a Healthy Sex Drive
  •     Helps with Hot Flashes, Mood Swings, and Decreased Energy
  •     Eases Nervousness, tension and irritability
  •     Promotes Weight Maintenance and Weight Loss

Menersa is an all-natural, non-prescription product that balances hormone levels and negates the symptoms of menopause, including relieving hot flashes, mood swings, and nervousness. Menersa contains no artificial hormones, and is not a synthetic formulation. Menersa does not produce the adverse side effects that occur with chemical or prescription drugs.

REVIVE: one of the largest surveys of postmenopausal women published online in the Journal of Sexual Medicine, FOR IMMEDIATE RELEASE,

A new survey of more than 3,000 postmenopausal women reveals that women living with vulvar and vaginal atrophy (VVA) are either unaware of what causes this progressive and chronic condition, or are simply dissatisfied with the therapies available. The REVIVE survey (REal Women’s VIews of Treatment Options for Menopausal Vulvar/Vaginal ChangEs) exposed multiple barriers to the treatment of VVA, including lack of knowledge, reluctance to discuss symptoms and disappointment with current therapies.

Some symptoms of VVA include painful intercourse, vaginal dryness and vaginal irritation. The REVIVE survey findings were published online in the Journal of Sexual Medicine. Findings from this survey, the largest of its kind, have important implications as women are living longer and will spend up to one-third of their lives post menopause. In fact, an estimated 32 million postmenopausal women in the United States (U.S.) experience symptoms of VVA.

“A women’s sexual health post menopause is an important aspect of her overall, general health and is therefore too important to ignore. I would like to see more women talking to their healthcare professionals about this very real medical condition so they can find a treatment option for them,” said Sheryl A. Kingsberg, Ph.D., Clinical Psychologist, Case Western Reserve University School of Medicine and REVIVE survey author. “In this survey, many women reported that VVA has an impact on their lives – particularly their intimate relationships. Despite this, almost half of the women admitted to not discussing symptoms with their healthcare professionals because they were embarrassed or felt the topic was too difficult to discuss. This signals a need for increased awareness and communication.”

The REVIVE survey also revealed that despite the widespread impact of this condition, 62 percent of women in the survey said they are “not at all familiar” with VVA and only 24 percent attributed VVA symptoms to menopause. More importantly, women who have been diagnosed with VVA report being dissatisfied with current treatment options. These respondents were using over-the-counter (OTC) lubricants/moisturizers or prescription vaginal products. The vaginal route of administration was identified as a limitation by 39 percent of all participants. Those using prescription vaginal treatments reported a dislike of application procedures and disruption of sexual spontaneity.

The development of educational programs that foster dialogue between postmenopausal women and their healthcare professionals (HCPs) may help raise awareness and improve management of this prevalent condition.

About the REVIVE Survey The REVIVE survey was conducted using a large cohort of postmenopausal women in the U.S. who reported having VVA and/or other symptoms consistent with VVA. Women aged 45 to 75 years who were members of the KnowledgePanel®, a nationwide online 56,000-member panel developed and maintained by GfK Knowledge Networks, were invited to participate. Participants completed the survey between May 31, 2012 and June 14, 2012. Panel members were awarded points for their participation redeemable for merchandise, gift cards or cash.

The survey included 3,046 participants, the largest U.S. cohort of menopausal women. Of this cohort, 1,145 women (38 percent) had experienced VVA symptoms in the previous month, and 45 percent and 53 percent, respectively, had experienced VVA symptoms in the previous three and six months. A comprehensive online questionnaire was developed with input and collaboration from a panel of clinicians and researchers in menopause and sexual health, and approved by The Western Institutional Review Board. The REVIVE survey was sponsored/funded by Shionogi Inc., the U.S.-based company of Shionogi & Co., Ltd.

About Vulvar and Vaginal Atrophy (VVA)  Vulvar and vaginal atrophy (VVA) is a chronic and progressive condition caused by decreased estrogen levels. Declining estrogen levels during menopause can cause tissues of the vaginal lining to grow thinner and to lose elasticity. Menopause also causes increases in vaginal pH. These physiological signs that characterize aging of the vagina can lead to moderate to severe dyspareunia (painful intercourse), a symptom of VVA due to menopause.

About Shionogi Shionogi Inc. is the U.S.-based subsidiary of Shionogi & Co., Ltd., headquartered in Osaka, Japan. Shionogi & Co., Ltd. is a major research-driven pharmaceutical company dedicated to placing the highest value on patients. Shionogi’s research and development currently targets three therapeutic areas: women’s health, infectious diseases, pain, and metabolic syndrome. In addition, Shionogi is engaged in new research areas such as allergy and cancer. Contributing to the health of patients around the world through development in these therapeutic areas is Shionogi’s primary goal. For more details, please visit For more information on Shionogi Inc., headquartered in Florham Park, NJ, please visit


Q: My boyfriend and I have been together seven years. I’m 50 and he’s 60. I have many health issues. Until recently, we’ve got great sex, but this time our intimacy life has dwindled. He has a strong sex drive.
We argue about that so much. I’ve lost interest and it also pains. Whenever we do have intercourse, I have tears coming out of my eyes, simply because it pains me, but I want to please him. (I’m not into oral intercourse either.) I was able to go the rest of my life without intercourse and be happy. Can you assist? I truly do love him; I just don’t like intimacy any longer.
A: You’re at an age when you’re possibly suffering from peri-menopause, so that you’re still getting your periods, so that you aren’t menopausal but you’re beginning to get some of the signs and symptoms of the menopause. The 1 that’s key here is a reducing of your natural vaginal lubrication. If perhaps you’re not generating as much as necessary lubrication, then intercourse will certainly because you pain. The option is to use an artificial lubricant to supplement your own.
Of course the fear that intercourse is going to be painful is going to reduce your interest in intercourse, but if you can solve the issue with some lubrication, then your libido should recover. If that doesn’t work, consult your gynecologist. While hormone replacement therapy is not as generally suggested as it once was, there are hormones that you can securely take only to boost your natural lubrication. Let me understand what happens.

Q: What are tips to assist my man clean up after intercourse?
A: Let’s begin with the concept that the aftereffects of getting intercourse, primarily his ejaculate, are natural products and shouldn’t be looked at with disgust. I can understand couples not wanting to soil the sheets, but it might be much better for your intercourse life if you put down a large towel underneath you, and then you wouldn’t need to worry very much about cleaning up.
I’m not against cleaning up, mind you, but some individuals rush into it, and that eliminates from after play, the hot feelings that ladies specifically enjoy from just being cuddled after intercourse. Understanding that the only factor which will need washing is the towel may remove some of your sensation the need to cleanup immediately.

Q: I need motivation for new intercourse and foreplay postures. I am twenty four, I may be getting married very soon and I don’t want the spark to burn out.
A: While several variety is essential to maintaining the spark alive, the primary intimate organ is your mind, therefore keeping the relationship sparkling is what really will make your intercourse life sparkle, more than simply using new postures.
If you go out to see a movie or play that tickles your intellect and then go for a drink afterward and speak about it, discussing what was in the piece and what you both consider this, when you get back you’re going to get good intercourse because you 1st associated with each other’s thoughts. But when you’re sitting around watching the same old boring TV shows and then want to get intercourse, it won’t really matter which postures you recommend — the odds are that the intercourse also will be boring. Foreplay doesn’t start when you 1st enter into bed, but long before that, therefore prepare yourself for intercourse by making the full night as stimulating as possible.

Women who have a history of depression have an earlier onset of the perimenopause, according to a study. The perimenopause is the time period immediately before the menopause proper begins, when a woman might experience some menstrual irregularities and symptoms like depression.

ImageResearchers at Brigham and Women’s Hospital in the US have been looking at whether depression is a risk factor for early perimenopause. They studied a group of 332 women with a history of major depression and 644 women with no such history. All were aged between 36 and 45 and had not begun the menopause. Blood samples were taken to assess ovarian function and the women monitored to see when the perimenopause or menopause began.

Those with a history of depression were more likely to begin the perimenopause at an earlier age, and to experience some depressive symptoms. In fact, women with severe depression taking medication had three times the risk of early perimenopause. The study didn’t look at whether menopause itself occurred earlier – it may be that the depressed women also have a longer perimenopause. The health implications could be serious – for women with a history of depression could be exposed to estrogen deficiency for longer, which would increase the risk of heart disease, cognitive decline and osteoporosis in later life. They may also be at higher risk of a recurrence of their depression.


i cool is a health supplement for the menopause. Most of these supplants are formulated to effectively reduce hot flashes as well as night sweats. i cool + D is usually provided with Vitamin supplement D for the hot flashes signs and symptoms and benefits of bone building. It contains several well-known ingredients which are liable to provide clinically tested rest from hot flashes and night sweats.

What are the active ingredients of I-cool:

It contains thirty mg of geniVida. This is the main component of this supplement. GeniVida is a non-soy genistein and is very effective to solve menopausal issues. It truly is a nature identical having the identical chemical structure just as organic from genistein. It shows their benefit within 7 to eight weeks of consistent usage. i cool depends on geniVida non-soy genistein and does not carry black cohosh, soy, estrogen, oi-cool
r even further body chemicals.

How does i cool work?

At the time of and after the menopause, a woman’s estrogen levels drop.

This fall usually brings on uncomfortable symptoms such as hot flashes, night sweats and mood changes, as well as the sudden reduction in bone that can result in bone health issues.

The natural genistein in i cool combats this drop in estrogen and alleviates, if not eliminates depressed menopausal signs. i cool contains natural genistein just like geniVida has long been clinically proven to preserve bone mineral strength and composition in post-menopausal females.

How long does it take to work?

A medical research reveals that i-cool reduced hot flashes by an average of 28% after 4 weeks. In the clinical research, measurements were initially taken after four weeks, so there is no official amount of time showing when i cool will begin to function, but will vary from person to woman. A number of people see improvement in one to two weeks, but we ask for you to allow for 1 to 2 months for maximum results. It will be highly suggested that clients use one pill per day, since i-cool works via cumulative effect.

Is it harmful to take more than one pill per day?

The dosage for i-cool is only one tablet a day, which may be taken either in the morning or the evening. geniVida, the dietary ingredient in i-cool, has had numerous protection studies. they possess almost all shown that geniVida is safe when the recommended serving is taken It is strongly recommended that you simply consult your medical care specialist to find out if taking a number of tablet a day is acceptable for your individual situation.

Amberen Review

Amberen is the brand for a blend of components established and promoted by Luanda Biomedical and offered for sale in capsule form off the shelf to menopausal females.  The medication relieves signs and symptoms usually related to the symptoms of menopause. Woman employs to assist publicize and help support hormonal stability. This product helps to control hot flashes, insomnia, irritation, weight gain and so more. There are no known negative affects you may consult your physician to see whether this product will work for you.

Amberen Ingredients:Amberen

  • Ammonium Succinate
  • Calcium Disuccinate
  • Monosodium L-Glutamate
  • Glycine
  • Magnesium Disuccinate Hydrate
  • Zinc Difumarate Hydrate
  • Tocopherol Acetate/Vitamin E

How Does It Work?

Amberen encourages the hypothalamus, enhancing communication between it and the mind. This, in return, “normalizes” the performance of the ovaries in addition to adrenal glands and also promotes hormone and enzyme production, resulting in an alleviation of menopausal symptoms. Amberen is a helpful prescription for many females.

What are the benefits?

  • The natural ingredients aid in achieving getting rid of mood swings, night sweats, hot flashes, etc. without causing any side-effects.
  • There is a thirty day money back guarantee.
  • A support services number has been given on the official website.
  • There is free of cost phone consultation with nurse for Amberen clients.

Recommended Use:

Amberen is available in a pill form which is suggested to take as a 90 day course. The Amberin packet includes a self-assessment exam which will advise you on if you should take two capsules per day or four. Nearly all women will find noticeable outcome within around 3 to 4 weeks. Amberen truly does fulfill all of the Good Manufacturing practices and will show a very lengthy track record for 40 years of safety in the state of Los Angeles, California.

Bottom Line:

Amberen product is examined on animals for its performance; however the official website will likely not reveal the exact amount of the ingredients it contains. Other natural menopause relief supplements can also be found so it is recommended to review regarding those and choose the ideal product.  There are various products available in the market which is not contain mineral oil, petroleum and never tested on animal like Menoquil, Emerita Menopause Plus Formula etc.